211 research outputs found

    Residual impact of topsoil removal and soil amendments on crop productivity over sixteen years

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    Non-Peer ReviewedSoil erosion remains a threat to our global soil resource. This study was conducted to ascertain the effects of simulated erosion on soil productivity and methods for its amendment. Incremental depths (0, 5, 10, 15 and 20 cm) of surface soil or cuts were mechanically removed to simulate erosion at two sites (one dryland, one irrigated) in southern Alberta in 1990. Three amendment treatments (nitrogen + phosphorus fertilizer, 5 cm of topsoil, or 75 Mg ha-1 of feedlot manure) and a check were superimposed on each of the cuts. The sites were cropped annually until 2006. On average, sixteen year yield reductions were 10.0 % for 5 cm, 19.5 % for 10 cm, 29.0 % for 15 cm and 38.5 % for 20 cm of topsoil removal. Average grain yield loss was 50 kg ha-1 cm-1 yr-1 at the Dryland site and 59 kg ha-1 cm-1 yr-1 at the Irrigated site. Amendments ranked manure > topsoil > fertilizer in terms of restoring productivity to the desurfaced soils. The study reinforces the need to prevent erosion and indicates that application of livestock manure is an option for restoring soil productivity in the short term

    The influence of simulated erosion on crop growth and the value of topsoil in soil productivity

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    Non-Peer ReviewedWind erosion is a major soil degradation phenomenon on the Canadian prairies but its effects on soil productivity are not well quantified. In the spring of 1990, incremental depths of soil (0, 5, 10, 15 and 20 cm) were removed with an excavator, to simulate wind erosion at four sites (three dryland and one irrigated) in southern Alberta. Highly significant non-linear relationships were found between the depth of de-surfacing and subsequent spring wheat grain yields showing that simulated erosion drastically reduced soil productivity. Treatment effects at the irrigated site followed the same trend as the dryland site illustrating that topsoil loss cannot be compensated by adequate soil moisture. The 0-1 cm increment of topsoil was worth more (in terms of magnitude of yield loss when it was removed) on the irrigated site followed by the Black, Dark Brown, and Brown dryland soils

    Analysis of Farm Development in Dutch Agriculture and Horticulture

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    This paper analysis the effects of farmer characteristics, farm structure and farm performance on farm renewal and farm growth. The data set used in this research consists of panel data from the Dutch Farm Accountancy Data Network of farms specialized in plant production extended with a data from survey among those farms. Probit models were used to determine the likelihood of the changes. Results show that the degree of mechanization increases the probability of farm growth and farm renewal. Family labour input and solvency have a negative impact on farm growth. Farm size is positively correlated with farm renewal. No indications of the influence of the life cycle have been found.decision making, diversification, farm growth, farm structure, innovation, panel data, Crop Production/Industries, Farm Management,

    Characterization of an endogenous gene expressed in Aedes aegypti using an orally infectious recombinant Sindbis virus

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    Sindbis virus expression vectors have been used successfully to express and silence genes of interest in vivo in several mosquito species, including Aedes aegypti, Ae. albopictus, Ae. triseriatus,Culex pipiens, Armigeres subalbatus and Anopheles gambiae. Here we describe the expression of an endogenous gene, defensin, in Ae. aegypti using the orally infectious Sindbis virus, MRE/3′2J expression vector. We optimized conditions to infect mosquito larvae per os using C6/36 Ae. albopictus cells infected with the recombinant virus to maximize virus infection and expression of defensin. Infection with the parental Sindbis virus (MRE/3′2J) did not induce defensin expression. Mosquito larvae infected by ingestion of recombinant Sindbis virus-infected C6/36 cells expressed defensin when they emerged as adults. Defensin expression was observed by western analysis or indirect fluorescent assay in all developmental stages of mosquitoes infected with MRE/3′2J virus that contained the defensin insert. The multiplicity of infection of C6/36 cells and the quantity of infected cells consumed by larvae played an important role in defensin expression. Parental viruses, missing the defensin insert, and/or other defective interfering virus may have contributed to these observations

    Dynamic Vortex Phases and Pinning in Superconductors with Twin Boundaries

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    We investigate the pinning and driven dynamics of vortices interacting with twin boundaries using large scale molecular dynamics simulations on samples with near one million pinning sites. For low applied driving forces, the vortex lattice orients itself parallel to the twin boundary and we observe the creation of a flux gradient and vortex free region near the edges of the twin boundary. For increasing drive, we find evidence for several distinct dynamical flow phases which we characterize by the density of defects in the vortex lattice, the microscopic vortex flow patterns, and orientation of the vortex lattice. We show that these different dynamical phases can be directly related to microscopically measurable voltage - current V(I) curves and voltage noise. By conducting a series of simulations for various twin boundary parameters we derive several vortex dynamic phase diagrams.Comment: 5 figures, to appear in Phys. Rev.

    An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

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    For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

    Meta-analysis of type 2 Diabetes in African Americans Consortium

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    Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies (GWAS) in individuals of European ancestry. In order to investigate the genetic architecture of T2D in African Americans, the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium examined 17 GWAS on T2D comprising 8,284 cases and 15,543 controls in African Americans in stage 1 analysis. Single nucleotide polymorphisms (SNPs) association analysis was conducted in each study under the additive model after adjustment for age, sex, study site, and principal components. Meta-analysis of approximately 2.6 million genotyped and imputed SNPs in all studies was conducted using an inverse variance-weighted fixed effect model. Replications were performed to follow up 21 loci in up to 6,061 cases and 5,483 controls in African Americans, and 8,130 cases and 38,987 controls of European ancestry. We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 × 10(-94)<P<5 × 10(-8), odds ratio (OR)  = 1.09 to 1.36). Fine-mapping revealed that 88 of 158 previously identified T2D or glucose homeostasis loci demonstrated nominal to highly significant association (2.2 × 10(-23) < locus-wide P<0.05). These novel and previously identified loci yielded a sibling relative risk of 1.19, explaining 17.5% of the phenotypic variance of T2D on the liability scale in African Americans. Overall, this study identified two novel susceptibility loci for T2D in African Americans. A substantial number of previously reported loci are transferable to African Americans after accounting for linkage disequilibrium, enabling fine mapping of causal variants in trans-ethnic meta-analysis studies.Peer reviewe

    ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

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    This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA's activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive, and psychosocial factors
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